This is a tragic real story of what can happen with pharmaceutical companies testing new drugs on real people.
In 2006, a drug company developed a new medication for the treatment of cancers, code-named as "TGN1412". Pre-clinical studies, especially on animals (rodents and monkeys) showed no toxic responses, so the company moved to human trials on 6 healthy male volunteers. Two people were in the control group and 4 received the medication.
Within about 1 hour, those who got the medication were having severe allergy-like reactions, which resulted in headaches, nausea, vomiting, difficulty breathing, high fever, muscle pain, organ failure, low blood pressure and blood clotting symptoms... Sound familiar?!
All volunteers were transferred to intensive care hospitals , where one person died, and others lost limbs from clotting issues or permanent organ damage, or other major health complications.
This particular medical trial resulted in the European Medicines Agency to change the guidelines for testing drugs in humans. The tragic events in this trial serve as a reminder that animal trials do not confirm safety in humans, or that becoming a volunteer for medical trials for new and experimental medications or vaccines is not worth risking your life for...
Despite the dangers and effects of the medication, another company is continuing research on this medication.
This story is relevant for a couple of reasons:
1) The major manufacturers of the recent un-named vaccines skipped clinical trials on animals and went straight into testing on human volunteers with simultaneous production of their vaccines
2) Animal trails often find issues with the medications or vaccines before they are tested on humans, but humans are NOT the same as rats or monkeys, with different physiological and biochemical responses. Hence a medication or vaccine which appears to work in animals may not in humans
3) The current vaccine manufacturers have documented their "Phase 3 clinical trials" as still being current, until 2022 or 2023... meaning that the population who are getting their vaccines ARE their guinea pigs - THEY are the clinical trial.
This true situation has resulted in a movie (called "The Facility") being loosely based on what happened. A BBC documentary on this tragic story is also available to watch.
Stay healthy. Don't mess with nature - your immune system knows what to do!
References:
Here's more on the story - https://www.mirror.co.uk/news/uk-news/how-six-fit-young-men-9860903
Many studies on the drug, called "TGN1412" can be found here:
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/tgn1412
In 2006, a drug company developed a new medication for the treatment of cancers, code-named as "TGN1412". Pre-clinical studies, especially on animals (rodents and monkeys) showed no toxic responses, so the company moved to human trials on 6 healthy male volunteers. Two people were in the control group and 4 received the medication.
Within about 1 hour, those who got the medication were having severe allergy-like reactions, which resulted in headaches, nausea, vomiting, difficulty breathing, high fever, muscle pain, organ failure, low blood pressure and blood clotting symptoms... Sound familiar?!
All volunteers were transferred to intensive care hospitals , where one person died, and others lost limbs from clotting issues or permanent organ damage, or other major health complications.
This particular medical trial resulted in the European Medicines Agency to change the guidelines for testing drugs in humans. The tragic events in this trial serve as a reminder that animal trials do not confirm safety in humans, or that becoming a volunteer for medical trials for new and experimental medications or vaccines is not worth risking your life for...
Despite the dangers and effects of the medication, another company is continuing research on this medication.
This story is relevant for a couple of reasons:
1) The major manufacturers of the recent un-named vaccines skipped clinical trials on animals and went straight into testing on human volunteers with simultaneous production of their vaccines
2) Animal trails often find issues with the medications or vaccines before they are tested on humans, but humans are NOT the same as rats or monkeys, with different physiological and biochemical responses. Hence a medication or vaccine which appears to work in animals may not in humans
3) The current vaccine manufacturers have documented their "Phase 3 clinical trials" as still being current, until 2022 or 2023... meaning that the population who are getting their vaccines ARE their guinea pigs - THEY are the clinical trial.
This true situation has resulted in a movie (called "The Facility") being loosely based on what happened. A BBC documentary on this tragic story is also available to watch.
Stay healthy. Don't mess with nature - your immune system knows what to do!
References:
Here's more on the story - https://www.mirror.co.uk/news/uk-news/how-six-fit-young-men-9860903
Many studies on the drug, called "TGN1412" can be found here:
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/tgn1412
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